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NAD MAKES HISTORY

Nicotinamide Adenine Dinucleotide (NAD) is a coenzyme that is extensively researched because of its central role in many biological functions. In recent years, scientific studies and clinical trials have paved the way for a single molecule to become one of the most important discovery in medicine

STUDIES INVOLVING NAD ARE SKYROCKETING. MORE THAN 50 000 RELATED PUBLICATIONS ARE AVAILABLE ON PUBMED, COVERING MAJOR DESEASES AND METABOLIC DISORDERS.

NAD IS A UNIVERSAL KEY COMMUNICATION MOLECULE

NAD is crucial for enzymatic reactions in every living cells. From the simplest bacteria to humans, life could not exist without NAD. That is why NAD is one of the most researched molecules in biology and medicine.

NAD IS CRUCIAL FOR YOUR CELLS

NAD is at the center of many vital functions such as converting the energy from the food into the energy the body needs (ATP), DNA Repair (PARP1), SIRTUINs activation, telomere maintenance, neurotransmitter function, extracellular signaling and more.

NMN AND NAD, THE INTIMATE RELATIONSHIPS

NMN, AN OUTSTANDING PRECURSOR

NMN is a precursor, which means a molecular building blocks of NAD: when in the cells NMN is rapidly used to form NAD. NMN is both available in the bloodstream, and, once inside a cell, able to bypass the rate‐limiting enzyme in NAD production, which makes it the perfect NAD precursor.

THE NMN TRANSPORTER

NMN is directly transported from the bloodstream into the cells by a special protein called sic98c. In vivo NMN is absorbed from the gut into blood circulation within 2–3 min and transported into tissues within 10–30 min. NMN is then immediately utilized for NAD+ biosynthesis, significantly increasing NAD+ content in tissues over 60 min. In short, NMN is easily uptaken in the cells throughout the body, which is not the case of the other precursors, such as NR (commercially named NIAGEN), Nicotinamide and Niacin.

QUERCETIN, A POWERFUL SENOLYTIC

A senolytic is a molecule able to selectively induce death of senescent cells and consequently improve lifespan in humans. Senescent cells accumulate in many tissues with aging and at sites of pathology in multiple chronic diseases. Quercetin is a polyphenol found in many fruits, vegetables, leaves, and grains, known to improve metabolic health by activating longevity genes. Studies and clinical trials with various doses have have been proven to improve physical functions and increase lifespan.

HUMAN STUDIES ABOUT NMN & QUERCETIN

NMN
QUERCETIN